As women age, estrogen levels tend to gradually decrease, which is a normal physiological process.
Menopause is a natural stage in a woman's life where ovarian function gradually declines, leading to reduced estrogen secretion.
Weight gain is associated with increased estrogen levels in fat tissue, whereas a reduction in body fat can lead to lower estrogen levels.
Chronic diseases such as hypothyroidism, diabetes, and hypertension can affect hormone balance.
Some women may experience premature ovarian failure before the age of 40, resulting in decreased estrogen levels.
Once a woman stops having children, her estrogen levels may be affected.