Several diseases can increase the risk of uremia by progressively damaging kidney function:
This is one of the most common causes of uremia. Chronic glomerulonephritis gradually reduces the filtering function of the glomeruli.
Poorly controlled long-term diabetes can lead to hardening of the renal arterioles, affecting the filtration function of the glomeruli.
Long-term high blood pressure may cause hardening of the renal arterioles, reducing blood supply to the kidneys and impairing their function.
This hereditary condition leads to the formation of many cysts in the kidneys, which may eventually cause kidney failure.
Diseases like lupus nephritis, an autoimmune condition, can cause chronic kidney damage.
Conditions such as Alport syndrome and Fabry disease can lead to structural or functional kidney damage.