If a pulmonary nodule shows persistent growth in follow-up imaging examinations, it may indicate malignant transformation.
Malignant pulmonary nodules often have irregular, spiculated, or lobulated margins.
If the pulmonary nodule is accompanied by persistent coughing, sputum production, hemoptysis, chest pain, or difficulty breathing, further evaluation may be necessary.
Unexplained weight loss can be a common symptom of various cancers, including lung cancer.
If imaging examinations reveal abnormal enlargement of lymph nodes near the pulmonary nodule, it may be a sign of cancer metastasis.
Unexplained persistent fever may be related to cancer.
If the nodule shows mixed ground-glass opacity or solid components in CT scans, it may indicate malignant potential.