High uric acid levels can lead to the deposition of uric acid crystals in the joints, causing acute gout attacks characterized by severe joint pain.
Affected joints may become red, warm, and tender to the touch.
Stiffness in the affected joints can make movement difficult.
Some gout patients may develop red, painful rashes near the joints or on the skin, known as tophi.
Hyperuricemia can affect the kidneys, leading to gouty nephropathy. Symptoms may include dark urine, painful urination, reduced urine output, or proteinuria.
Chronic hyperuricemia may be associated with metabolic syndrome, increasing the risk of heart disease, hypertension, and diabetes.
Although fatigue is not a primary symptom of gout, hyperuricemia may be related to feelings of tiredness.